Date of Award
Spring 4-1-2024
Document Type
Distinction Paper
Degree Name
Biochemistry and Molecular Biology-BS
Department
Chemistry
Advisor
Dr. Carrigan Hayes
First Committee Member
Dr. Dean Johnston
Second Committee Member
Dr. Steffanie Burk
Keywords
Organic Chemistry, Steric Hindrance, Stereochemistry
Abstract
This project examines how steric hindrance in the starting materials affects the stereochemical outcomes of the cis and trans isomers formed as products by the Wittig reaction for a variety of settings. These effects were studied using experimental data such as NMR spectroscopy. A set of twelve total reactions was run, using different aldehydes and Wittig salts reacted under a variety of conditions to compare E:Z ratios of the isomers formed.
Licensing Permission
Copyright, all rights reserved. Fair Use
Acknowledgement 1
1
Acknowledgement 2
1
Recommended Citation
Marchi, Amanda, "Optimizing Synthetic Routes to (E)- and (Z)- Stilbenes via Mechanistic Explorations of the Wittig Reaction" (2024). Undergraduate Distinction Papers. 115.
https://digitalcommons.otterbein.edu/stu_dist/115