Nursing Student Class Projects (Formerly MSN)
Academic Term
Summer 2022
Document Type
Project
Course Number
6810
Course Name
Advanced Pathophysiology for the Advanced Practice Nurse
Professor’s Name
Dr. Deana Batross and Dr. Shivani Bhatnagar
Keywords
Aortic Stenosis, Pathogenesis, Pathophysiology, Treatment options, Significance of disease process, Nursing Implications
Subject Categories
Cardiovascular Diseases | Cardiovascular System | Circulatory and Respiratory Physiology | Immune System Diseases | Medical Pharmacology | Medical Physiology | Pathological Conditions, Signs and Symptoms | Physiological Processes
Abstract
Pathophysiology of Aortic Stenosis
Melissa J. Lee
Department of Nursing, Otterbein University
NURS 6810: Advanced Pathophysiology for the Advanced Practice Nurse
Dr. Deana Batross & Dr. Shivani Bhatnagar
July 29, 2022
Pathophysiology of Aortic Stenosis
Proper evaluation of co-morbidities is imperative for patient safety and successful outcomes for patients undergoing anesthesia. Aortic stenosis (AS) is one of the most complex diseases encountered in anesthesia, affecting five percent of older adults and ten percent of the 80-89-year-old-cohort (Joseph et al., 2017). The pathophysiological development of AS is the end result of an inflammatory process caused by endothelial damage from mechanical stress, accumulation of lipid and calcium deposits, and the subsequent leaflet thickening and valvular narrowing (Joseph et al., 2017). Additionally, myocardial thickening is seen in AS, requiring a compensatory increase in afterload to maintain coronary perfusion (Zheng et al., 2020). Optimization of perioperative risk factors is required to avoid serious intraoperative hemodynamic complications. Understanding the signs and symptoms of disease as well as pathological processes of aortic stenosis is paramount to providing safe and effective anesthetic care based on well-defined hemodynamic goals. The goal of this poster presentation on aortic stenosis is to describe the pathophysiology, symptoms, treatment modalities and considerations for healthcare providers as it relates to the management of these patients.
References
Joseph, J., Naqvi, S. Y., Giri, J., & Goldberg, S. (2017). Aortic stenosis: pathophysiology, diagnosis, and therapy. The American Journal of Medicine, 130(3), 253–263. https://doi.org/10.1016/j.amjmed.2016.10.005
Zheng, K. H., Tzolos, E., & Dweck, M. R. (2020). Pathophysiology of aortic stenosis and future perspectives for medical therapy. Cardiology Clinics, 38(1), 1–12. https://doi.org/10.1016/j.ccl.2019.09.010
Licensing Permission
Copyright, all rights reserved. Fair Use
Recommended Citation
Lee, Melissa, "Pathophysiology of Aortic Stenosis" (2022). Nursing Student Class Projects (Formerly MSN). 508.
https://digitalcommons.otterbein.edu/stu_msn/508
Included in
Cardiovascular Diseases Commons, Cardiovascular System Commons, Circulatory and Respiratory Physiology Commons, Immune System Diseases Commons, Medical Pharmacology Commons, Medical Physiology Commons, Pathological Conditions, Signs and Symptoms Commons, Physiological Processes Commons