Nursing Student Class Projects (Formerly MSN)
Title
Academic Term
Summer 7-26-2022
Document Type
Project
Course Number
N6810
Course Name
Advanced Pathophysiology for the Advanced Practice Nurse
Professor’s Name
Dr. Batross & Dr. Bhatnagar
Keywords
MH, Malignant, Hyperthermia, Dantrolene, Malignant Hyperthermia, Ryanodine
Subject Categories
Medicine and Health Sciences | Nursing
Abstract
Malignant Hyperthermia
Christina Bensley
Department of Nursing, Otterbein University
NURS 6810: Advanced Pathophysiology for the Advanced Practice Nurse
Dr. Batross and Dr. Bhatnagar
August 5th, 2022
Abstract
Malignant Hyperthermia (MH) is a rare genetic mutation of the skeletal muscle that induces a hypermetabolic response when patients are exposed to volatile inhaled anesthetics or depolarizing neuromuscular blockers (Weant & Gregory, 2021). The first case of MH was identified in 1960, with an estimated mortality rate of 70-80% without appropriate treatment (Hopkins et al., 2021). Perioperative care providers must be able to identify triggering agents, recognize presenting signs and symptoms, and know how to manage the state to prevent life-threatening complications (Kleidon, 2020). MH is a rare and complex state that requires adequate training and education to achieve the best possible outcome for the patient. MH results in rapidly increasing body temperature that requires immediate interventions to prevent permanent injury or death. Early recognition and proactive planning are vital in the successful management of a patient experiencing clinical symptoms of MH. Therefore, the healthcare provider must have a complete comprehension of this pharmacogenetic disorder to ensure that the safest, most effective care is provided to the patient.
References
Hopkins, P. M., Girard, T., Dalay, S., Jenkins, B., Thacker, A., Patteril, M., & McGrady, E.
(2021). Malignant hyperthermia 2020: Guideline from the Association of
Anaesthetists. Anaesthesia, 76(5), 655–664. https://doi.org/10.1111/anae.15317
Kleidon, C. (2020). Malignant hyperthermia in a regional facility: A case study. Journal of
Perioperative Nursing, 33(1), 33–37. https://doi.org/10.26550/2209-1092.1076
Weant, K. A., & Gregory, H. (2021). Pathophysiology and Treatment of Malignant
Hyperthermia. Advanced Emergency Nursing Journal, 43(2), 102–110. https://doi.org/10.1097/TME.0000000000000344
Licensing Permission
Copyright, all rights reserved. Fair Use
Recommended Citation
Bensley, Christina, "Malignant Hyperthermia" (2022). Nursing Student Class Projects (Formerly MSN). 495.
https://digitalcommons.otterbein.edu/stu_msn/495