Date of Award

Spring 5-1-2022

Document Type


Degree Name

Doctor of Nursing Practice (DNP)




Dr. Kacy Ballard

First Committee Member

Dr. Brian Garrett

Second Committee Member

Ms. Stormy Barton

Third Committee Member

Ms. Elizabeth Finke


Antibiotic-Associated, Clostridium Difficile, Cdiff, Diarrhea, Nosocomial, Probiotics

Subject Categories

Medicine and Health Sciences


Clostridium difficile (C. difficile) are toxigenic, spore-forming bacteria that live in the gastrointestinal (GI) tract of healthy individuals without harm to the host due to the protection offered by the natural intestinal flora. Antibiotics can disrupt the intestinal flora and create an environment within the GI tract that promotes the infectious growth of C. difficile. C. difficile infections (CDIs) are the most common cause of antibiotic-associated diarrhea, are highly contagious, and can result in an increased risk of morbidities and mortality to individuals affected. Recent studies and literature reviews identified the use of probiotic therapy in patients receiving antibiotics to be an effective prophylactic intervention for decreasing antibiotic-associated CDI occurrence. The purpose of this organizational assessment was to compile organizational data concerning nosocomial CDIs as a prerequisite to future practice changes regarding the use of probiotics for the prevention of nosocomial antibiotic-associated CDIs. Results to be determined upon completion of data collection and analysis. Conclusions & recommendations to be determined upon completion of data collection and analysis.

Licensing Permission

Copyright, all rights reserved. Fair Use



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