Document Type
Article
Publication Date
3-3-2017
Publication Title
Peptides
Publisher
Elsevier, Inc
Keywords
Opioid peptides, Physical Training, Endurance exercise, Strength
Abstract
Due to the important interactions of proenkephalin fragments (e.g., proenkephalin [107–140] Peptide F) to enhance activation of immune cells and potentially combat pain associated with exercise-induced muscle tissue damage, we examined the differential plasma responses of Peptide F to different exercise training programs. Participants were tested pre-training (T1), and after 8 weeks (T2) of training. Fiftynine healthy women were matched and then randomly assigned to one of four groups: heavy resistance strength training (STR, n = 18), high intensity endurance training (END, n = 14), combined strength and endurance training (CMB, n = 17), or control (CON, n = 10). Blood was collected using a cannula inserted into a superficial vein in the antecubital fossa with samples collected at rest and immediately after an acute bout of 6 X 10 RM in a squat resistance exercise before training and after training. Prior to any training, no significant differences were observed for any of the groups before or after acute exercise. With training, significant (P ≤ 0.95) elevations were observed with acute exercise in each of the exercise training groups and this effect was significantly greater in the CMB group. These data indicate that in untrained women exercise training will not change resting of plasma Peptide F concentrations unless both forms of exercise are performed but will result in significant increases in the immediate postexercise responses. Such findings appear to indicate adrenal medullary adaptations opioid production significantly altered with exercise training.
First Page
26
Last Page
32
Volume
91
Repository Citation
DuPont, William H.; Kraemer, William J.; Nindl, Bradley C.; Lee, Elaine C.; Fragala, Maren S.; Hatfield, Disa L.; Caldwell, Lydia K.; Post, Emily M.; Beeler, Matthew K.; Volek, Jeff S.; and Maresh, Carl M., "The effects of different exercise training modalities on plasma proenkephalin Peptide F in women" (2017). Health and Sport Sciences Faculty Scholarship. 35.
https://digitalcommons.otterbein.edu/hsports_fac/35
Original Citation
William H. DuPont, William J. Kraemer, Bradley C. Nindl, Elaine C. Lee, Maren S. Fragala, Disa L. Hatfield, Lydia K. Caldwell, Emily M. Post, Matthew K. Beeler, Jeff S. Volek, Carl M. Maresh, The effects of different exercise training modalities on plasma proenkephalin Peptide F in women, Peptides, Volume 91, 2017, Pages 26-32, ISSN 0196-9781, https://doi.org/10.1016/j.peptides.2017.02.006. (https://www.sciencedirect.com/science/article/pii/S0196978117300475) Abstract: Due to the important interactions of proenkephalin fragments (e.g., proenkephalin [107–140] Peptide F) to enhance activation of immune cells and potentially combat pain associated with exercise-induced muscle tissue damage, we examined the differential plasma responses of Peptide F to different exercise training programs. Participants were tested pre-training (T1), and after 8 weeks (T2) of training. Fifty-nine healthy women were matched and then randomly assigned to one of four groups: heavy resistance strength training (STR, n=18), high intensity endurance training (END, n=14), combined strength and endurance training (CMB, n=17), or control (CON, n=10). Blood was collected using a cannula inserted into a superficial vein in the antecubital fossa with samples collected at rest and immediately after an acute bout of 6 X 10 RM in a squat resistance exercise before training and after training. Prior to any training, no significant differences were observed for any of the groups before or after acute exercise. With training, significant (P≤0.95) elevations were observed with acute exercise in each of the exercise training groups and this effect was significantly greater in the CMB group. These data indicate that in untrained women exercise training will not change resting of plasma Peptide F concentrations unless both forms of exercise are performed but will result in significant increases in the immediate post-exercise responses. Such findings appear to indicate adrenal medullary adaptations opioid production significantly altered with exercise training. Keywords: Opioid peptides; Physical training; Endurance exercise; Strength
DOI
10.1016/j.peptides.2017.02.006
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