Nursing Student Class Projects (Formerly MSN)

Academic Term

Summer 2015

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

John D. Chovan, James R. Cacchillo


Thyroid Disease, Hypothyroidism, Autoimmune Disease

Subject Categories

Endocrine System Diseases | Medical Pathology | Medicine and Health Sciences | Nursing


Thyroid disease is a general term utilized to describe a variety of conditions affecting the thyroid gland, including hypothyroidism, the deficient production of thyroid hormone; hyperthyroidism, the excess production of thyroid hormone; and goiter, the physiologic swelling of the thyroid gland (Cihakova, 2001; Warren, 2014). Primary hypothyroidism is the most prevalent thyroid disease in the United States, most frequently occurring as a result of chronic autoimmune thyroiditis, specifically Hashimoto’s Disease (Warren, 2014). Hashimoto’s disease (HD), also known as Hashimoto’s thyroiditis and human autoimmune thyroiditis, was named after Hakaru Hashimoto, a Japanese medical scientist who first described the condition in 1912 (Cihakova, 2001). HD is a chronic autoimmune condition characterized by the presence of lymphocytic infiltration, serum autoantibodies, and destruction of thyroid tissue; as a result, hypothyroidism often ensues (Liu et al., 2014; Warren, 2014).



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