Master of Science in Nursing (MSN) Student Scholarship

Date Written

Summer 2015

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

John D. Chovan, James R. Cacchillo


Unconjugated Bilirubin, Newborns, ABO Incompatibility

Subject Categories

Medical Pathology | Medicine and Health Sciences | Nursing


Neonatal jaundice is a common condition present in infants after birth. It is caused by elevated bilirubin in the blood. It can affect up to 84% of term infants and is one of the most common cause for hospital readmission for the neonatal department (Muchowski, 2014). It typically appears within 24 hours of life and is normally present in otherwise healthy newborns. Physiologic jaundice, also known as unconjugated bilirubin, is a normal process that happens in neonates because the hepatic system is not matured yet (Kirk, 2008). Majority of the time physiologic jaundice resolves on its own. Pathological jaundice, also known as conjugated bilirubin, in newborns is due to other reasons other than the normal pathologic process the newborn hepatic system goes through. It may be a result of endocrine or genetic disorders, which are considered to be rare (Kirk, 2008). A more common cause is due to ABO incompatibility. For the purpose of this poster the focus is going to be on pathologic elevated bilirubin specifically related to ABO incompatibility between mother and baby.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.