Master of Science in Nursing (MSN) Student Scholarship

Date Written

Summer 2015

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

John D. Chovan, James R. Cacchillo


Inflammatory Arthritis, Atrial Fibrillation, Case Studies

Subject Categories

Cardiovascular Diseases | Medical Pathology | Medicine and Health Sciences | Nursing


Gout, an inflammatory arthritis caused by elevated serum uric acid levels, is emerging as a significant risk factor for cardiovascular disease (CVD). Recently, a nurse practitioner (NP) was caring for a patient who was suffering from a particularly severe gout attack while being treated in the ICU for new onset Atrial Fibrillation. The patient reported that he had never had an attack this severe before. He asked the NP if his history of gout could be related to his recent heart problems. The nurse practitioner, in order to answer the patient’s question, spent time researching the disease process of gout, as well as, the possibility of association between gout and cardiovascular disease. She learned that current research provides clear evidence that gout is a risk factor for CVD. In the course of her research, she advanced her knowledge of the pathophysiology of gout and the significance of gout’s risk for CVD. Finally, utilizing this knowledge will help her t



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