Nursing Student Class Projects (Formerly MSN)

Academic Term

Summer 2015

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

John D. Chovan, James R. Cacchillo


Septic Shock, Children

Subject Categories

Bacterial Infections and Mycoses | Medical Pathology | Medicine and Health Sciences | Nursing


Sepsis and more specifically septic shock in the pediatric population is a diagnosis that is full of complexities. There are instances where a neutropenic oncology patient observes a better outcome than a previously healthy patient who is suffering from the same pathogen related sepsis. Sepsis is the 10th leading cause of death according to the Center for Disease Control and Prevention, and each year between 20,000 and 42,000 children are diagnosed with severe sepsis (Riley & Wheeler, 2012). Even with significant advances in medical treatment, sepsis is still associated with high morbidity and mortality rates. A retrospective study of patient outcomes across 26 countries found that pediatric sepsis mortality was 25%, was seemingly unaffected by age, and had only mild variations across developed countries. Of the survivors, 20% suffered from a form of moderate functional disability (Weiss et al., 2015). Despite the amount of clinical trials and research associated with pediatric sepsis its incidence continues to increase by close to 1.5% annually (Riley & Wheeler, 2012).



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