Master of Science in Nursing (MSN) Student Scholarship

Date Written

Fall 2014

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

John D. Chovan, James R. Cacchillo


Lung Diseases, IPF

Subject Categories

Medical Pathology | Nursing | Respiratory Tract Diseases


Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible lung disease, characterized by chronic inflammation and fibroproliferation of the parenchymal cells of the lung that lead to chronic respiratory failure and ultimately death (Kotsianidis et al., 2009). IPF is more prevalent in men than in women and risk for disease increases after age 60. IPF is the most common form of idiopathic interstitial pneumonia and it affects over 100,000 persons in the United States alone (Ding et al., 2011). Most of IPF cases are considered to be unpredictable and sporadic in nature, however approximately 15-20% of cases have a family history of IPF and linked to autosomal dominance disorder (Tsang, Wyatt, Ting, & Beattie, 2012). IPF is a debilitating disease with minimal treatment options and current research is being done to determine treatments that will optimize patient’s lung capacity and improve quality of life. Though efforts are being made to decrease morbidity and mortality of this disease IPF remains to have a poor prognosis because it responds very little to medications and other treatments. Median survival after diagnosis is two to three years (Putman, Rosas, & Hunninghake, 2014).



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