Nursing Student Class Projects (Formerly MSN)

Academic Term

Summer 8-2020

Document Type


Course Number

NURS 6810

Course Name

Advanced Pathophysiology for the Advanced Practice Nurse

Professor’s Name

Dr. John Chovan & Dr. Sue Butz


Heart Failure with reduced EF, Pathophysiology of heart failure, Physics of heart failure, HFrEF, Left sided heart failure

Subject Categories

Medicine and Health Sciences | Nursing


Heart failure (HF) is a complex disease the requires a high-level understanding of pathophysiology and physics. Heart failure is an umbrella term with multiple subsets beneath it. Heart failure with reduced ejection fraction relates to a failing left ventricle with an ejection fraction (EF) of less than 40%. Inability to push fluid forward causes the heart rate to increase, neurohormonal changes and creates a backup of flow into the lungs creating dyspnea. Applied physics plays a large role in understand heart failure. Frank-starling’s curve, Ohm’s, Poiseulle’s and Laplace’s laws all apply to the physiological principles behind preload, afterload, and contractility. Medications continue to improve side effects however the gold standard in treatment is a heart transplant. Nurses need to have a full understanding of hemodynamics, physics, and pathophysiology of heart failure in order to recognize and intervene with deteriorating heart failure conditions. Heart failure is never going to be eradicated; however, the understanding of the disease process, prescribed treatments, and interventions need to continue to improve to save more lives.

Keywords: Heart Failure with Reduced EF, pathophysiology of heart failure, physics in heart failure, HFrEF, Left sided Heart failure

Included in

Nursing Commons



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