Nursing Student Class Projects (Formerly MSN)

Academic Term

Summer 2020

Document Type


Course Number

NURS 6810

Course Name

Advanced Pathophysiology for the Advanced Practice Nurse

Professor’s Name

Dr. John Chovan & Dr. Sue Butz


Pulmonary arterial hypertension, diagnosis, pathophysiology, classification of pulmonary arterial hypertension

Subject Categories

Critical Care Nursing | Medicine and Health Sciences | Nursing


Pulmonary arterial hypertension (PAH), is diagnosed as persistently elevated pressures in the pulmonary arteries. It is a severe disease that requires early diagnosis and treatment as it can be life-threatening if not treated promptly and adequately. The initial presenting signs and symptoms such as lethargy, malaise, and exercise intolerance can be vague, making it difficult to diagnose. Also, doctors at centers that specialize in treating PAH are the only ones who can properly diagnose the condition and initiate disease-targeted therapy. There are different types of PAH; the World Health Organization (WHO) recognizes 5 groups of pulmonary hypertension (PH), and they are (1) PAH, (2) PA due to left heart disease, (3) PH due to lung disease, or hypoxia, (4) chronic thromboembolic PAH, and (5) PH with unclear multi-factorial means. Also, the WHO recognizes 4 functional classes of PH. Functional Class I is considered to be the mildest form of the disease, and class IV is the most severe. The condition is complex and leads to right heart failure, causing a more complicated clinical syndrome that affects multiple organs, including the heart, liver, brain, and kidney.



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