Nursing Student Class Projects (Formerly MSN)

Academic Term

Summer 2020

Document Type


Course Number

NURS 6810

Course Name

Advanced Pathophysiology for the Advanced Practice Nurse

Professor’s Name

Dr. John Chovan, Dr. Sue Butz


irritable bowel syndrome, IBS, pathophysiology of irritable bowel syndrome, gut microbiome, functional gastrointestinal disorder, Rome IV criteria

Subject Categories

Medicine and Health Sciences | Nursing


Past understanding of the pathophysiology of irritable bowel syndrome (IBS) presents this chronic condition as a functional gastrointestinal disorder related to psychological causes. While no structural abnormalities are present in IBS, this poorly understood condition of persistent abdominal pain and altered bowel habits can be debilitating, contributing to a decreased quality of life. Current research has uncovered new evidence, that for many patients, symptoms may actually originate in the gut. An altered gut microbiome is now accepted as playing a central role in the development of the disorder. This poster summarizes the current pathophysiological concepts of IBS, including the role of the gut microbiome, psychological associations, visceral hypersensitivity, genetic influence and food sensitivities. IBS is prevalent and commonly encountered in the primary care setting. Nurse practitioners will have opportunities to improve the outcomes of these patients. Utilizing the Rome IV criteria and Bristol stool form scale, patients can be spared unnecessary tests to achieve a definitive diagnosis. With many probable causes that continue to evolve, management of the disorder is challenging. Maintaining a current understanding of this complex disorder will contribute to the best outcomes.

Included in

Nursing Commons



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