Nursing Student Class Projects (Formerly MSN)

Academic Term

Summer 2020

Document Type


Course Number

NURS 6810-OL1

Course Name

Advanced Pathophysiology for the Advanced Practice Nurse

Professor’s Name

John Chovan PhD, DNP, RN, APRN-CNP, APRN-CNS, Sue Butz DNP, RN, CCRN-K


Sepsis, Pathophysiology, Septic Shock, Infection

Subject Categories

Medicine and Health Sciences | Nursing


Sepsis is a life threatening emergency and it is the body’s extreme response to an infection (CDC, 2019). Sepsis continues to be a problem for all medical institutions globally due to its high mortality rate. Sepsis can be caused by any pathogen and may arise from pneumonia, urinary tract infections and infections in the skin or soft tissue (Nagalingam, 2018). As sepsis progresses, it can lead to organ dysfunction, tissue damage and death. The progression of sepsis can be categorized in 3 stages, that is Systemic Inflammatory Response Syndrome (SIRS), severe sepsis and septic shock. Septic shock is the most serious stage and has a mortality rate as high 50% (Ryding, 2018). Time is an important factor in managing sepsis, early recognition and early initiation of treatment impacts the survival rates of sepsis patients.

Included in

Nursing Commons



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.