Nursing Student Class Projects (Formerly MSN)

Academic Term


Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

Dr. John D. Chovan


Sickle Cell Anemia, Red Blood Cells, Complication, Mutation, Inherit, Crisis

Subject Categories

Medicine and Health Sciences | Nursing


Sickle cell anemia (SCA) is an inherited autosomal recessive disorder of red blood cell caused by an abnormality of hemoglobin called sickle hemoglobin (HbS) (Centers for Disease Control and Prevention (CDC), 2017). African countries carry the highest incident of individuals with the SCA(CDC, 2017). In the United State, approximately 1 in 12 African-Americans carry the trait for SCA, and 1 of every 350 African-American infants born have the disorder (CDC, 2017). Individuals with sickle cell disease exhibit significant morbidity and mortality. Clinical manifestations of SCA are chronic hemolysis and acute vaso-occlusive crisis, which causes severe pain, infections, and chronic organ damage (CDC, 2017). Currently, newborn screening, early medical intervention, parents education, penicillin, and vaccination prophylaxis have successfully reduced morbidity and mortality rate. This poster gives an extensive review of pathophysiological processes of SCA, with specific details to its signs, symptoms and complications, underlying pathophysiology, and the significance of the pathophysiology. The poster also presents implication for nursing care.

Included in

Nursing Commons



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