Dr. John Chovan, PhD., DNP, RN, CNP, CNS
Vascular, Endothelial, Glycocalyx, Surface Layer
Medicine and Health Sciences | Nursing
Vascular endothelial glycocalyx is a fragile, gel-like substance found on the inside of the luminal wall of blood vessels. When damaged, either by hyperglycemia, hypoxia, hypervolemia, or inflammation, this fragile structure is degraded leaving the endothelium exposed. Damaged endothelial glycocalyx causes many side effects including edema, blood vessel vasodilation, and coagulopathy. Despite the lack of treatment options, treating the underlying cause and preventing degradation by avoiding triggers is paramount in reducing morbidity and mortality.
Potts, Morgan, "Underappreciation of Endothelial Glycocalyx" (2018). Master of Science in Nursing (MSN) Student Scholarship. 301.