Nursing Student Class Projects (Formerly MSN)
Title
Academic Term
Fall 2014
Document Type
Project
Course Number
NURS 5330
Course Name
Advanced Pathophysiology
Professor’s Name
John D. Chovan, James R. Cacchillo
Keywords
Hypermetabolic Muscular Disorders, Autosomal Dominant Disorders
Subject Categories
Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Medical Pathology | Musculoskeletal Diseases | Nursing
Abstract
Malignant hyperthermia (MH) is an autosomal-dominant disorder that is inherited. The disturbance of calcium homeostasis associated with MH affects skeletal muscle (Schneiderbanger, Johannsen, Roewer, & Schuster, 2014). This hypermetabolic muscular disorder is triggered by exposure to depolarizing muscle relaxants such as succinylcholine or inhaled halogenated volatile anesthetics such as sevoflurane, halothane, desflurane, enflurane, and isoflurane (Stratman, Flynn, & Hatton, 2009). In susceptible individuals, this potentially lethal syndrome may cause hyperthermia, hypercapnia, muscular rigidity, hypoxemia, acidosis, tachycardia, and hyperkalemia (Schneiderbanger et al., 2014).
Recommended Citation
Weberding, Eric, "Malignant Hyperthermia" (2014). Nursing Student Class Projects (Formerly MSN). 20.
https://digitalcommons.otterbein.edu/stu_msn/20
Included in
Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, Medical Pathology Commons, Musculoskeletal Diseases Commons, Nursing Commons