Master of Science in Nursing (MSN) Student Scholarship

Date Written

Summer 7-28-2016

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

Dr. Chovan


Hepatorenal, Cirrhosis, Kidney Failure, Portal Hypertension, Spontaneous Bacterial Peritonitis

Subject Categories

Medicine and Health Sciences | Nursing


Type 1 hepatorenal syndrome is kidney failure that occurs in advanced cirrhosis (Fagundes & Ginès, 2012). It is characterized by a, “significant reduction in creatinine clearance within 1-2 weeks of presentation” (Bacon, 2015). Patients that develop this condition have a median survival rate of one month (Dameron, 2011). Vasodilation leads to decreased perfusion to the kidneys and thus kidney injury (Boyer et al., 2011). Liver transplantation is the best treatment for hepatorenal syndrome (Fagundes & Ginès, 2012). Common causes of cirrhosis are hepatitis C infection, alcohol consumption, and fatty liver disease (Warner, Cuthbert, Bhore, & Rockey, 2011). Regardless of the cause of cirrhosis, the progression of hepatorenal syndrome once identified is extremely quick and deadly.

Included in

Nursing Commons



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