Master of Science in Nursing (MSN) Student Scholarship

Date Written

Summer 7-25-2016

Document Type


Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

Dr. John Chovan


Aortic, Valve, Stenosis, Calcific, Pathophysiology, Disease

Subject Categories

Medicine and Health Sciences | Nursing


A recent influx of patients undergoing the transcatheter aortic valve replacement (TAVR) procedure sparked interest in the pathophysiologic process of Aortic Stenosis (AS), especially in the geriatric population. AS is mostly asymptomatic until later stages of the disease, which delays treatment and intervention leading to poor outcomes and prognosis, especially for those who are not surgical candidates. The TAVR procedure has allowed patients who are otherwise not candidates for open heart surgery undergo valve replacement in a low risk fashion, prolonging life and improving quality of life. AS causes an increase in afterload, decreasing outflow of blood from the left ventricle. This process can lead to an array of complications including left sided heart failure. The underlying pathophysiologic process of AS will be outlined in this presentation.

Included in

Nursing Commons



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.