Master of Science in Nursing (MSN) Student Scholarship

Date Written

Fall 2014

Document Type

Project

Course Number

NURS 5330

Course Name

Advanced Pathophysiology

Professor’s Name

John D. Chovan, James R. Cacchillo

Keywords

Kidney Diseases, Genetic Disorders, Renal Failure

Subject Categories

Endocrine System Diseases | Medical Pathology | Nursing

Abstract

Alport syndrome is rare genetic disorder of the glomerulus in the kidneys that can be X-linked, Autosomal recessive, or Autosomal dominant in nature. Clinical manifestation includes hearing loss, hematuria, proteinuria, and hypertension (Cheungpasitporn, Kaewpoowat, Suksaranjit, Kittanamongkolchai, Srivali, Ungprasert, & Rangan, 2012). It is most common disease in males. A 24-hour urine specimen is usually obtained to check for proteinuria and elevated creatinine, which indicate acute renal failure (Cosgrove, 2012). A renal biopsy and ultrasounds is used to confirm the diagnosis of Alport Syndrome. Patients that are diagnosed with such disease require dialysis and referral to an ophthalmology and audiology. The following poster will help in understanding the signs and symptoms, pathophysiology, and nursing implication of Alport syndrome based on information found in literature research.

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