Nursing Student Class Projects (Formerly MSN)
Title
Academic Term
Fall 2014
Document Type
Project
Course Number
NURS 5330
Course Name
Advanced Pathophysiology
Professor’s Name
John D. Chovan, James R. Cacchillo
Keywords
Blood Diseases, Anemia
Subject Categories
Hemic and Lymphatic Diseases | Medical Pathology | Nursing
Abstract
Hereditary Spherocytosis (HS) is a hemolytic anemia where red blood cell membranes are spherical unlike common red blood cells, which are flat and round. In individuals with HS the spleen does not recognize these amorphous cells and destroys—rather filters—them them, making the individual anemic (MedlinePlus, 2013). HS is an autosomal dominant, or recessive autosomal inherited blood disease (Huq, Pietroni, Rahman & Alam, 2010) HS happens in 1 in 2,000 of the Caucasian population in or from Northern Europe (MedlinePlus, 2013). The proteins involved in HS are ankyrin-1, ά-spectrin, β-spectrin, band 3, and protein 4.2. Hyperbilirubinemia is a common symptoms in neonates with HS. According to Christensen and Henry (2010) hyperbilirubinemia is sometimes miss as a diagnose for HS (Christensen & Henrym 2010).
Recommended Citation
Loeser, Dolores, "Hereditary Spherocytosis" (2014). Nursing Student Class Projects (Formerly MSN). 21.
https://digitalcommons.otterbein.edu/stu_msn/21